The objective of ISES is to develop ICT building blocks to integrate, complement and empower existing tools for design and operation management (FM) to a Virtual Energy Lab. This will allow evaluating, simulating and optimizing the energy efficiency of products for built facilities and facility components in variations of real life scenarios before their realization, acknowledging the stochastic life-cycle nature. The focus of the prototype application domain is on buildings, factories and warehouses because in buildings about 40% of the global energy is used and 30% of CO2 emissions and solid waste is created. There is a huge market for more energy-efficient design of new buildings and for refurbishing of the huge building stock through energy-efficient component products. The goal of the project is to increase, by an order of magnitude, the quality of energy-efficiency in design through the development of an In-Silico Energy Simulator Laboratory, based on an interoperable ontology-supported platform.